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An Anatomical Solution in Hypospadias Surgery: The GFC Technique

A surgical method based on the natural anatomy of the penis and urethra, designed to reduce the risk of fistula and stenosis, and also applicable in cases of recurrent hypospadias.

GFC Technique

The GFC (Glanular-Frenular Collar) technique is a groundbreaking anatomical approach in modern hypospadias surgery.In hypospadias surgery, tubularization of the neourethra over a catheter or stent and approximation of the dissected glans wings on the midline to enclose the neourethra have been the standard surgical method for decades. However, the male urethra is not a tubular structure with uniform configuration and diameter. The “fossa navicularis” (terminal/glanular portion of the male urethra) has distinct attachments with the “septum glandis” and “frenulum”. Recently, we documented the anatomical features of the glans penis with MRI study. In accordance with previous historical drawings of the glans penis, our findings revealed that a fibrous tissue (septum glandis) covers the glanular urethra (fossa navicularis) circumferentially. It binds the fossa navicularis to the frenulum and corpus cavernosum, as a suspensory ligament on the midline. Hence, it may be true to say that reconstruction of the glanular urethra has been far from its normal anatomical features for decades.

Functional anatomy of the glans penis and glanular urethra: Cross-sections of the glans penis showing the fibroelastic fibrous tissue (septum glandis) surrounding the fossa navicularis: *Note how the corpus spongiosum gradually terminates at the mid-glanular (middle glans) level and is replaced by the septum glandis. Upper (*) and lower (**) median septum and frenulum (y) (Henle). B) Schematic description of the glans penis and urethra (Özbey).
Functional anatomy of the glans penis and glanular urethra: Cross-sections of the glans penis showing the fibroelastic fibrous tissue (septum glandis) surrounding the fossa navicularis: *Note how the corpus spongiosum gradually terminates at the mid-glanular (mid-glans) level and is replaced by the septum glandis. Upper (*) and lower (**) median septum and frenulum (y) (Henle). B) Schematic description of the glans penis and urethra (Özbey).
MRI section of the penis showing the “septum glandis” (lower median septum) between the glans wings
MRI section of the penis showing the “septum glandis” (lower median septum) between the glans wings

As the most anatomical repair, the GFC technique respects the natural features of the glanular urethra and delivers the most effective and satisfying results in hypospadias.

— Journal of Pediatric Urology, 2017;13:34e1–34e6

The GFC technique is a turning point in hypospadias surgery, which is based on the anatomical features of the penis that are not taken into account since decades. With the GFC technique, the anatomical features of the glanular urethra, in particular the “fossa navicularis”, “septum glandis”, “frenulum” and the “shape of the normal urine stream” are taken into account for the first time. As being the most anatomical repair, the GFC technique gives the most effective and satisfactory results in hypospadias. In normal human penis anatomy, the corpus spongiosum covers the urethra up to the mid-glanular (sub-coronal) level. After that level, a fibrous tissue (septum glandis) surrounds the glanular urethra (fossa navicularis), separates the two hemiglans, connects the upper and lower median septum and holds the glanular urethra in the midline as a suspensory ligament. The glans wings are separated by the ‘septum glandis’ and a ventral cleft between the glans wings that accommodates the frenulum, which is epidermally lined extension of the septum. Hence, the ‘septum glandis’ and frenulum are also included in the formation of the distal (glanular and subcoronal) urethra.

A) Dr. Friedrich Gustav Jacob Henle defines the (***) fibroelastic fibrous tissue surrounding the fossa navicularis as "septum glandis", and its extensions as the upper (*) and lower (**) median septum and frenulum (y). B) Penile MRI images: showing the same anatomical structures and extensions (upper median septum) of the structure (large arrow), also known as the "distal ligament" or "corporo-glans ligament".
A) Dr. Friedrich Gustav Jacob Henle defines the (***) fibroelastic fibrous tissue surrounding the fossa navicularis as "septum glandis", and its extensions as the upper (*) and lower (**) median septum and frenulum (y). B) Penile MRI images: showing the same anatomical structures and extensions (upper median septum) of the structure (large arrow), also known as the "distal ligament" or "corporo-glans ligament".

In addition to a defective urethra and its corpus spongiosum, the ‘septum glandis’ and frenulum are entirely missing in hypospadias. The foreskin is not fused ventrally; it appears as a hood over the glans penis. Recent studies have shown that masculinization of the urethral plate occurs in association with the growth and fusion of the preputial fold along the ventral midline of the genital tubercle, which also forms the frenulum of the proximal part of the glanular urethra. Therefore, it is clear that formation of a normal glanular urethra, with its fossa navicularis, ‘septum glandis’ and frenulum are important indicators of an anatomical hypospadias reconstruction. This has inspired a hypospadias repair technique (GFC:Glanular-Frenular Collar technique) that simulates the development of the glanular and subcoronal urethra, which can be incorporated into the repair of all cases of hypospadias. The GFC technique involves reconstruction of the septum glandis, which has been overlooked in the history of hypospadias, and formation of the frenulum, creating the ventral wall of the glanular urethra without dissecting the glans, leaving room for the formation of the navicular fossa. The GFC technique aims to restore the functional anatomy of the glans, replicating the embryologic development of the glanular urethra.

 
Anatomical modeling of the foreskin (preputium) for glanular hypospadias reconstruction.
Anatomical modeling of the foreskin (preputium) for glanular hypospadias reconstruction.

Because of centuries-long misconceptions in repairing the male urethra, hypospadias surgery has become a complex procedure.

— Traditional misconceptions in hypospadias surgery, J Pediatr Surg, 2026

The GFC technique allows a tension-free tubularization of the glanular urethra, afforded by the limited spongioplasty. The space provided for the reformation of the fossa navicularis is supported by loose connective tissue (septum and frenulum) ventrally. The ventral aspect of the glans penis should not be covered (compounded) by the glans wings over its full length, in order to accommodate the frenulum. The GFC technique doesn’t necessitate glans dissection, is neither limited, nor extensive. Subepithelial approximation has been found to be anatomically and physiologically sufficient. With the GFC technique, normal urine flow (wave-like shape) is obtained in all patients. The detailed anatomy of any organ and/or malformation can be further defined based on new knowledge, as in hypospadias. The anatomical differences between the glanular and penile urethra, the structures such as the septum glandis and the fossa navicularis are new definitions that have led to a paradigm shift in hypospadias. The finding that the wings of the glans are not fused together ventrally but are separated by the septum glandis represents a new insight and clarifies the causes of the complications that frequently occur in hypospadias, such as meatal stenosis, fistula and the so-called glans-dehiscence. Reconstruction of hypospadias should include the formation of a septum glandis, frenulum, and navicular fossa with a dual surgical approach for glanular and penile urethra reconstruction.

Glans penis detailed structural anatomy diagram
Although Dr. Özbey described the anatomy of the glans penis and urethra, the misinformation that continues to be published today and examples of Dr. Özbey's criticisms.
Although Dr. Özbey described the anatomy of the glans penis and urethra, the misinformation that continues to be published today and examples of Dr. Özbey's criticisms.
a & b: a) Changes in the configuration and cross-sectional area of ​​the proximal (A1) and glanular urethra (A2), along with changes in pressure (p) and velocity (v) in the urine flow. b) Velocity contours in an elliptical tube; It shows that there are lower speed losses in the major axis (Dr. J. Lekner).
a & b: a) Changes in the configuration and cross-sectional area of ​​the proximal (A1) and glanular urethra (A2), along with changes in pressure (p) and velocity (v) in the urine flow. b) Velocity contours in an elliptical tube; It shows that there are lower speed losses in the major axis (Dr. J. Lekner).

Hypospadias repair should include reconstruction of the septum glandis, frenulum and fossa navicularis through a dual surgical approach for the glanular and penile urethra.

— The GFC technique: dual approach to hypospadias reconstruction, J Pediatr Urol, 2024

Traditional misconceptions in hypospadias surgery. J Pediatr Surg, January, 2026 (PDF)

  1. The male urethra is not a straight, uniform tube, as reconstructed in all hypospadias repair techniques. It has the “fossa navicularis”, which forms the glanular urethra with specific functional properties. The glans is not an anterior extension or expansion of the corpus spongiosum, which gradually terminates at the mid-glanular level. A faulty development of the fossa navicularis indicates a malformation of the glans itself, manifesting as grooves of varying depth on the glans.

  2. The glans tissue does not completely enclose the navicular fossa, but is separated by the “septum glandis” along the ventral midline. Although there is no “glans fusion”, this has unfortunately been routinely achieved for decades during hypospadias surgery by dissecting the wings of the glans.

  3. The “septum glandis” is the fibroelastic tissue, which covers the fossa navicularis. As a fibroelastic partition, the septum glandis provides the elasticity and adaptive configuration of the glanular urethra during micturition and ejaculation. Together with the frenulum the septum glandis forms the ventral wall of the glanular urethra.

  4. The “distal ligament” contributes significantly to the flexibility and rigidity of the glans, particularly during sexual intercourse. A deep midline incision of the glans is equivalent to a direct visual internal urethrotomy, corresponding exactly to the position of the distal ligament, which has reportedly led to erectile dysfunction in patients following hypospadias repair. Apparently, grafting glans would have far more detrimental consequences.

Relationship between distal ligament and septum glandis connective tissue in the human penis
Relationship between distal ligament and septum glandis connective tissue in the human penis
Pre- and post-operative clinical appearance of a hypospadias patient operated on with the GFC technique. visual 3
Pre- and postoperative clinical appearance of a hypospadias patient operated on with the GFC technique. visual 4
Postoperative urine flow in wave form in a penoscrotal hypospadias patient repaired with the GFC technique
Visual of normal urine flow in wave form coming out of the urethra without stricture after GFC surgery 1
Normal urine flow in wave form coming out of the urethra without stricture after GFC surgery. Visual 2
Wave-like urine flow and clinical outcomes after GFC technique surgery
Preoperative and postoperative clinical appearance of a hypospadias patient operated on with the GFC technique. visual 1
Pre- and post-operative clinical appearance of a hypospadias patient operated on with the GFC technique. visual 2

Scientific References

This article was prepared by Prof. Dr. Hüseyin Özbey, a Pediatric Surgery and Pediatric Urology Specialist, based on medical literature. You can review all scientific publications by Prof. Dr. Hüseyin Özbey here.

 

  1. Özbey H, et al. Hypospadias repair with the GFC Technique. J Pediatr Urol 2017;13:34e1–34e6. DOI
  2. Özbey H, Kumbasar A. Glans wings are separated ventrally by the septum glandis and frenulum penis: MRI. Turk J Urol 2017;43:525–9. DOI · PMC
  3. Özbey H, Arlı OT. “Fossa navicularis” and “septum glandis”: a flow-control chamber for the male urethra? Med Hypotheses 2020;140:109642. DOI
  4. Özbey H. The mystery of Jacob Henle’s “septum glandis”. J Anat 2019;234:728–9. DOI
  5. Özbey H, Devecioğlu D, Staroverov O. A closer look at iatrogenic hypospadias. Andrologia 2020;53:e13803. DOI
  6. Özbey H. Anatomical modeling of the foreskin for the reconstruction of glanular hypospadias. J Pediatr Urol 2021;17:335–337. DOI
  7. Özbey H. The GFC technique: dual approach to hypospadias reconstruction. J Pediatr Urol 2024;20:539–540. DOI
  8. Özbey H. Boundary tissues and layers in the anatomy of the penis. J Pediatr Urol 2025;21:526–7. DOI
  9. Özbey H. Traditional misconceptions in hypospadias surgery. J Pediatr Surg 2026. DOI
Michelangelo Adem'in Yaratılışı Tablosu Uyarlaması - Hipospadias Cerrahisinde Sanat ve GFC Tekniği
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